Bioactivity | NH2-C6-ARC186 is a modified ARC186 (HY-153098) with NH2-C6, that can be coupled to other peptides or molecules. ARC186 is a aptamer and a highly potent complement inhibitor that function by blocking the convertase-catalyzed activation of C5[1]. |
Name | NH2-C6-ARC186 |
Molar Mass | 12881.00 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | -20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Reference | [1]. Aptamer therapeutics useful in the treatment of complement-related disorders. WO2006088888A2. |