| Bioactivity | NFF-3 TFA, the peptide, is a selective MMP substrate. NFF-3 TFA selectively binds to MMP-3 and MMP-10 to be hydrolyzed. NFF-3 TFA is also cleaved by trypsin, hepatocyte growth factor activator, and factor Xa. Label NFF-3 TFA with a CyDye pair, Cy3/Cy5Q, can produce fluorescence in cell assays to detect cell activity[1]. | ||||||
| Name | NFF-3 TFA | ||||||
| Sequence | Arg-Pro-Lys-Pro-Val-Glu-{Nva}-Trp-Arg-Lys(DNP)-NH2 | ||||||
| Shortening | RPKPVE-{Nva}-WR-{K(DNP)}-NH2 | ||||||
| Formula | C80H111F3N22O22 | ||||||
| Molar Mass | 1789.87 | ||||||
| Appearance | Solid | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
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| Reference | [1]. Giricz O, et al. Comparison of metalloproteinase protein and activity profiling. Anal Biochem. 2011 Feb 1;409(1):37-45. |