NF-κΒ activator 1_product_DataBase

CAS: 2387524-59-4 F: C16H11FN2O2S W: 314.33

NF-κΒ activator 1 is a potent NF-κΒ activator with an EC50 of 0.9 μM. NF-κΒ activator 1 induces superoxide dismut

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

NF-κΒ activator 1 is a potent NF-κΒ activator with an EC50 of 0.9 μM. NF-κΒ activator 1 induces superoxide dismutase (SOD)2 mRNA expression[1].

Invitro

NF-κΒ activator 1 (compound 32) (1 μM; 6 hours) induces SOD2 mRNA expression in SH-SY5Y neuroblastoma cells[1].

Name

NF-κΒ activator 1

CAS

2387524-59-4

Formula

C16H11FN2O2S

Molar Mass

314.33

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Mathew B, et al. Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-ҡB activators for the treatment of ALS [published online ahead of print, 2020 Oct 22]. Eur J Med Chem. 2020;112952

PeptideDB

NF-κΒ activator 1

CAS: 2387524-59-4 F: C16H11FN2O2S W: 314.33