| Bioactivity | NF-κB-IN-6 (Compound 3d) is an anti-inflammatory agent through the mechanism of decreasing the protein expressions of iNOS and COX-2 by suppressing NF-κB signaling pathway. NF-κB-IN-6 inhibits NO production in LPS-induced RAW264.7 cells with an IC50 of 23.1 μM[1]. |
| Target | IC50: 23.1 μM (NO production) |
| Name | NF-κB-IN-6 |
| Formula | C14H20N2O3 |
| Molar Mass | 264.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li SM, et al. Bioactivity Study of Tricyclic and Tetracyclic Genipin Derivatives as Anti-inflammatory Agents. Bioorg Chem. 2022 Sep;126:105881. |