| Bioactivity | NF-56-EJ40 hydrochloride is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almost no activity towards rat SUCNR1. NF-56-EJ40 hydrochloride has high affinity for humanized rat SUCNR1 with a Ki value of 17.4 nM[1]. |
| CAS | 2728500-80-7 |
| Formula | C27H31Cl2N3O3 |
| Molar Mass | 516.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Haffke M, et al. Structural basis of species-selective antagonist binding to the succinate receptor. Nature. 2019 Oct;574(7779):581-585. |
NF-56-EJ40 hydrochloride
CAS: 2728500-80-7 F: C27H31Cl2N3O3 W: 516.46
NF-56-EJ40 hydrochloride is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 o
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.