PeptideDB

ND-L11B TFA

CAS: F: C39H52F6N10O4 W: 838.89

ND-L11B TFA is a potent degrader of nuclear receptor binding SET domain protein 2 (NSD2) andRE-IIBP, with the DC50 of 1.
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity ND-L11B TFA is a potent degrader of nuclear receptor binding SET domain protein 2 (NSD2) and RE-IIBP, with the DC50 of 1.48 and 0.8 μM, the Dmax is closed to 80 %[1].
Formula C39H52F6N10O4
Molar Mass 838.89
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Linghao Hu, et al. Discovery of SET domain-binding primary alkylamine-tethered degraders for the simultaneous degradation of NSD2-long and RE-IIBP isoforms. Eur J Med Chem. 2025 Feb 5:283:117179.