| Bioactivity | NCGC00188636 is a novel covalent pyruvate kinase (PYK) inhibitor. NCGC00188636 blocks nucleotide binding to the active site of pyruvate kinase. NCGC00188636 can be used for the research of the metabolism of many organisms and cell types. |
| Invitro | NCGC00188636 (DBS) (50 μM) has inhibition activity for LmPYK in time-dependent manner[1]. |
| Name | NCGC00188636 |
| CAS | 1039980-33-0 |
| Formula | C14H9NO4S2 |
| Molar Mass | 319.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hugh P Morgan, et al. A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase. Biochem J. 2012 Nov 15;448(1):67-72. |