| Bioactivity | NC-R17 is a RSL3-based noncovalent GPX4 degrader, involving in Ferroptosis. NC-R17 exhibits anti-tumor activity, used for noncovalent GPX4 PROTACs design[1]. |
| Target | GPX4 |
| Name | NC-R17 |
| Formula | C53H67N7O7 |
| Molar Mass | 914.14 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zheng C, et al. Structure-activity relationship study of RSL3-based GPX4 degraders and its potential noncovalent optimization. Eur J Med Chem. 2023 Jul 5;255:115393. |