| Bioactivity | NAcM-OPT (hydrochloride) is a protein interaction inhibitor. NAcM-OPT (hydrochloride) can disrupt the interaction between DCN1 and UBC12, with an IC50 value of 80 nM. NAcM-OPT (hydrochloride) can protect keratinocytes from H2O2-induced cell damage by promoting autophagy[1][2]. |
| CAS | 2416146-10-4 |
| Formula | C23H30Cl3N3O |
| Molar Mass | 470.86 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Fang Y, et al. Targeting the DCN1-UBC12 protein-protein interaction: novel approaches and future directions. Future Med Chem. 2019 Nov;11(22):2869-2871. [2]. Xiong R, et al. NAcM-OPT protects keratinocytes from H2O2-induced cell damage by promoting autophagy. Ann N Y Acad Sci. 2024 Jul;1537(1):155-167. |
NAcM-OPT hydrochloride
CAS: 2416146-10-4 F: C23H30Cl3N3O W: 470.86
NAcM-OPT (hydrochloride) is a protein interaction inhibitor. NAcM-OPT (hydrochloride) can disrupt the interaction betwee
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