| Bioactivity | NAMPT activator-6 is a NAMPT activator, a regulatory molecule for the optical control system of NAMPT and NAD+. NAMPT activator-6 can be used to design efficient photoswitchable proteolysis-targeting chimeras (PS-PROTACs) to achieve up-down reversible regulation of NAMPT and NAD+ in a light-dependent manner and reduce the toxicity associated with inhibitor-based PS-PROTACs. PS-PROTAC can be used to achieve antitumor activity, NAMPT, and NAD+ modulation in vivo via optical manipulation[1]. |
| CAS | 2237267-86-4 |
| Formula | C17H21N5O3S |
| Molar Mass | 375.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cheng J, et al. Photoswitchable PROTACs for Reversible and Spatiotemporal Regulation of NAMPT and NAD. Angew Chem Int Ed Engl. 2024 Mar 18;63(12):e202315997. |
NAMPT activator-6
CAS: 2237267-86-4 F: C17H21N5O3S W: 375.45
NAMPT activator-6 is a NAMPT activator, a regulatory molecule for the optical control system of NAMPT and NAD+. NAMPT ac
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