| Bioactivity | NADI-351 is an orally active and potent Notch1 inhibitor that selectively disrupts Notch1 transcription complexes and reduces Notch1 recruitment to target genes. NADI-351 can be utilized in cancer research[1]. |
| CAS | 2503017-11-4 |
| Formula | C19H20FN5O4S2 |
| Molar Mass | 465.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Alvarez-Trotta A, et al. Pharmacological Disruption of the Notch1 Transcriptional Complex Inhibits Tumor Growth by Selectively Targeting Cancer Stem Cells. Cancer Res. 2021 Jun 15;81(12):3347-3357. |
NADI-351
CAS: 2503017-11-4 F: C19H20FN5O4S2 W: 465.52
NADI-351 is an orally active and potent Notch1 inhibitor that selectively disrupts Notch1 transcription complexes and re
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