| Bioactivity | NAAA-IN-3 (Compound 17a) is a potent and selective inhibitor of NAAA with an IC50 of 50 nM. NAAA is a cysteine amidase which preferentially hydrolyzes the endogenous biolipids palmitoylethanolamide (PEA) and oleoylethanolamide (OEA). NAAA-IN-3 has the potential for the research of inflammation and pain[1]. |
| Name | NAAA-IN-3 |
| CAS | 1831115-59-3 |
| Formula | C17H16N2O |
| Molar Mass | 264.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Malamas MS, et al. Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors. Bioorg Med Chem. 2020 Jan 1;28(1):115195. |
NAAA-IN-3
CAS: 1831115-59-3 F: C17H16N2O W: 264.32
NAAA-IN-3 (Compound 17a) is a potent and selective inhibitor ofNAAAwith an IC50 of 50 nM. NAAA is a cysteine amidase whi
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