| Bioactivity | N3-PEG3-vc-PAB-MMAE is a synthesized drug-linker conjugate for ADC that incorporates the MMAE (a tubulin inhibitor ) and 3-unit PEG linker. N3-PEG3-vc-PAB-MMAE shows potent antitumor activity. | ||||||
| Invitro | Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of Dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types. | ||||||
| Name | N3-PEG3-vc-PAB-MMAE | ||||||
| Formula | C67H109N13O16 | ||||||
| Molar Mass | 1352.66 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage |
*该产品在溶液状态不稳定，建议您现用现配，即刻使用。 |
N3-PEG3-vc-PAB-MMAE
CAS: F: C67H109N13O16 W: 1352.66
N3-PEG3-vc-PAB-MMAE is a synthesized drug-linker conjugate for ADC that incorporates the MMAE (a tubulin inhibitor ) and
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