N2-Methylguanosine-d3_product_DataBase

Bioactivity	N2-Methylguanosine-d3 is deuterium labeled N2-Methylguanosine (HY-111647). N2-methylguanosine is a modified nucleoside that occurs at several specific locations in many tRNA's.
Invitro	氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。 0 --> N2-Methylguanosine-d3 相关抗体:
Name	N2-Methylguanosine-d3
Formula	C11H12D3N5O5
Molar Mass	300.29
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Ginell SL, et al. Conformation of N2-methylguanosine, a modified nucleoside of tRNA. Biochem Biophys Res Commun. 1978 Oct 30;84(4):886-94.

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