Bioactivity | N-trifluoroacetyl-β-alanyl chloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
Invitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. |
Name | N-trifluoroacetyl-β-alanyl chloride |
CAS | 87639-76-7 |
Formula | C5H5ClF3NO2 |
Molar Mass | 203.55 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. |