| Bioactivity | N-terminally acetylated Leu-enkephalin is the N-terminally acetylated form of Leu-enkephalin. Leu-enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors. | ||||||
| Invitro | Enkephalins (met- , leu-enkephalin, and enkephalin 8) and dynorphins are two classes of opioid peptides found in the spinal dorsal horn. Mu, delta, and kappa are three major subtypes of opioid receptors. Enkephalins are putative endogenous ligands for delta opioid receptors, and dynorphins are endogenous ligands for the kappa opioid receptors. Three receptor types resembling the vertebrate δ- and κ-type opioid receptors have been characterized pharmacologically in nervous tissues (e.g. Ki=18.9 nM for Leu-enkephalin) and localized by autoradiography at CHH terminals in the SG of C. maenas[1]. | ||||||
| Name | N-terminally acetylated Leu-enkephalin | ||||||
| Sequence | Ac-L-Tyr-Gly-Gly-L-Phe-D-Leu-COOH | ||||||
| Shortening | Ac-LYGGLFDL-COOH | ||||||
| Formula | C30H39N5O8 | ||||||
| Molar Mass | 597.66 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
N-terminally acetylated Leu-enkephalin
CAS: F: C30H39N5O8 W: 597.66
N-terminally acetylated Leu-enkephalin is the N-terminally acetylated form of Leu-enkephalin. Leu-enkephalin is a five a
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