| Bioactivity | N-myristoyl-RKRTLRRL inhibits binding of PKC substrates. N-myristoyl-RKRTLRRL inhibits Ca2+- and phosphatidylserine (PS)-dependent histone phosphorylation with IC50 of 5 μM.? histone phosphorylation with IC50 of 80 μM[1][2]. |
| Name | N-myristoyl-RKRTLRRL |
| CAS | 152246-40-7 |
| Sequence | {Myr}-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu |
| Shortening | {Myr}-RKRTLRRL |
| Formula | C60H117N21O11 |
| Molar Mass | 1308.71 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. David K Crockett, et al. Identification of proteins from formalin-fixed paraffin-embedded cells by LC-MS/MS. Lab Invest. 2005 Nov;85(11):1405-15. [2]. C A O'Brian, et al. A novel N-myristylated synthetic octapeptide inhibits protein kinase C activity and partially reverses murine fibrosarcoma cell resistance to Adriamycin. Invest New Drugs. 1991 May;9(2):169-79. |
N-myristoyl-RKRTLRRL
CAS: 152246-40-7 F: C60H117N21O11 W: 1308.71
N-myristoyl-RKRTLRRL inhibits binding of PKC substrates. N-myristoyl-RKRTLRRL inhibits Ca2+- and phosphatidylserine (PS)
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