Bioactivity | N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule. N-dodecanoyl-L-Homoserine lactone (C12-HSL) aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[1]. | ||||||||||||
Invitro | Disruption of cell-cell communication or quorum sensing (QS) is considered a stimulating approach for reducing bacterial pathogenicity and resistance[1]. | ||||||||||||
Name | N-dodecanoyl-L-Homoserine lactone | ||||||||||||
CAS | 137173-46-7 | ||||||||||||
Formula | C16H29NO3 | ||||||||||||
Molar Mass | 283.41 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Borges A, et al. Furvina inhibits the 3-oxo-C12-HSL-based quorum sensing system of Pseudomonas aeruginosa and QS-dependent phenotypes. Biofouling. 2017 Feb;33(2):156-168. |