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N-Nitrosomorpholine-d4

CAS: 61578-30-1 F: C4H4D4N2O2 W: 120.14

N-Nitrosomorpholine-d4 is the deuterium labeled N-Nitrosomorpholine. N-Nitrosomorpholine is a nitrosamine that is sensit
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Bioactivity N-Nitrosomorpholine-d4 is the deuterium labeled N-Nitrosomorpholine[1]. N-Nitrosomorpholine is a nitrosamine that is sensitive to light. N-nitrosomorpholine is a strong animal carcinogen[2].
Invitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Name N-Nitrosomorpholine-d4
CAS 61578-30-1
Formula C4H4D4N2O2
Molar Mass 120.14
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. K D Brunnemann, et al. N-Nitrosomorpholine and Other Volatile N-nitrosamines in Snuff Tobacco. Carcinogenesis. 1982;3(6):693-6.