Bioactivity | N'-Nitro-D-arginine, a nitric oxide synthesis inhibitor, also is a vasodilator that relaxes the smooth muscles and increases blood flow to the penis, improving erections. N'-Nitro-D-arginine also inhibits neutrophil migration by blocking receptors for tumour necrosis factor alpha (TNFα) and interleukin 8 (IL8)[1]. | ||||||||||||
In Vivo | N'-Nitro-D-arginine (40 mg/kg) produces a significant increase in systolic blood pressure in the chronic, awake, instrumented sheep model[1]. | ||||||||||||
Name | N'-Nitro-D-arginine | ||||||||||||
CAS | 66036-77-9 | ||||||||||||
Formula | C6H13N5O4 | ||||||||||||
Molar Mass | 219.20 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
|
||||||||||||
Reference | [1]. C K Narkowicz, et al. Delayed recovery from NG-nitro-L-arginine in the conscious sheep. Clin Exp Pharmacol Physiol. 1991 Dec;18(12):843-6. |