| Bioactivity | N-Desmethyl rosiglitazone is a metabolite of Rosiglitazone (HY-17386), generated through demethylation by the cytochrome P450 enzyme system in liver microsomes. It retains partial PPARγ agonist activity and supports studies on the metabolism and pharmacokinetics of Rosiglitazone (HY-17386)[1]. |
| CAS | 257892-31-2 |
| Formula | C17H17N3O3S |
| Molar Mass | 343.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Calixto LA, et al. Simultaneous determination of rosiglitazone and its metabolites in rat liver microsomal fraction using hollow-fiber liquid-phase microextraction for sample preparation. J Sep Sci. 2010 Sep;33(17-18):2872-80. |
N-Desmethyl rosiglitazone
CAS: 257892-31-2 F: C17H17N3O3S W: 343.40
N-Desmethyl rosiglitazone is a metabolite of Rosiglitazone (HY-17386), generated through demethylation by the cytochrome
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