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N-Desmethyl Bedaquiline-d6

CAS: 2271264-26-5 F: C31H23D6BrN2O2 W: 547.52

N-Desmethyl Bedaquiline-d6 is the deuterium labeled N-Desmethyl Bedaquiline.
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Bioactivity N-Desmethyl Bedaquiline-d6 is the deuterium labeled N-Desmethyl Bedaquiline[1].
Invitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Name N-Desmethyl Bedaquiline-d6
CAS 2271264-26-5
Formula C31H23D6BrN2O2
Molar Mass 547.52
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.