N-Decanoyl cyclopentylamide_product_DataBase

Bioactivity	N-Decanoyl cyclopentylamide (C10-CPA) is a potent inhibitor of quorum sensing in Pseudomonas aeruginosa. N-Decanoyl cyclopentylamide interferes with expression of Pseudomonas aeruginosa virulence factors regulated by the las and rhl quorum-sensing systems. N-Decanoyl cyclopentylamide inhibits production of elastase, pyocyanin, and rhamnolipid and biofilm formation[1].
Invitro	N-Decanoyl cyclopentylamide (C10-CPA) 可抑制铜绿假单胞菌中的群体感应，其对 lasB-lacZ 和 rhlA-lacZ 表达的半数最大抑制所需的浓度分别为 80 μM 和 90 μM[1]。N-Decanoyl cyclopentylamide 还可抑制毒力因子的产生，包括弹性蛋白酶、绿脓素和鼠李糖脂，以及生物膜的形成，而不会影响铜绿假单胞菌 PAO1 的生长[1]。N-Decanoyl cyclopentylamide 通过抑制其反应调节剂 (LasR 和 RhlR) 与自诱导剂之间的相互作用来干扰 las 和 rhl 群体感应系统[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> N-Decanoyl cyclopentylamide 相关抗体:
CAS	540796-75-6
Formula	C15H29NO
Molar Mass	239.40
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Takenori Ishida, et al. Inhibition of quorum sensing in Pseudomonas aeruginosa by N-acyl cyclopentylamides. Appl Environ Microbiol. 2007 May;73(10):3183-8.

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