N-Butyl-N-(4-hydroxybutyl)nitrosamine

CAS: 3817-11-6 F: C8H18N2O2 W: 174.24

N-Butyl-N-(4-hydroxybutyl)nitrosamine is a potent mutagen that can cause high-level of mutagenesis specifically in the e

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Bioactivity	N-Butyl-N-(4-hydroxybutyl)nitrosamine is a potent mutagen that can cause high-level of mutagenesis specifically in the epithelial cells (urothelial) of the urinary bladder. N-Butyl-N-(4-hydroxybutyl)nitrosamine is used to induce bladder cancer in rodents[1].
In Vivo	N-Butyl-N-(4-hydroxybutyl)nitrosamine (BBN；0.05% 溶液，溶于饮用水；持续 2 周) 是小鼠和大鼠尿路上皮组织的强效诱变剂[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
CAS	3817-11-6
Formula	C8H18N2O2
Molar Mass	174.24
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Zhiming He, et al. Tissue-specific mutagenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine as the basis for urothelial carcinogenesis. Mutat Res. 2012 Feb 18;742(1-2):92-5.