Bioactivity | N-Benzoylcytidine is a substrate for uracil-cytidine kinase 1 (UCK1) and UCK2. N-Benzoylcytidine can be used to synthesize 2-OH protective groups for solid-phase RNA synthesis, as well as synthetic oligonucleotides for UV induction and targeted gene silencing in zebrafish embryos[1][2][3]. | ||||||||||||
CAS | 13089-48-0 | ||||||||||||
Formula | C16H17N3O6 | ||||||||||||
Molar Mass | 347.32 | ||||||||||||
Appearance | 固体 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Van Rompay AR, et al. Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases. Mol Pharmacol. 2001 May;59(5):1181-6. [2]. Semenyuk A, et al. Synthesis of RNA using 2 ‘-O-DTM protection. Journal of the American Chemical Society, 2006, 128(38): 12356-12357. [3]. Shestopalov IA, et al. Light-controlled gene silencing in zebrafish embryos. Nat Chem Biol. 2007 Oct;3(10):650-1. |