| Bioactivity | N-Arachidonoylserotonin (Arachidonyl serotonin; AA-5-HT) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 value of 1~12 µM. N-Arachidonoylserotonin acts also as an antagonist of transient receptor potential vanilloid-type 1 (TRPV1) channels (IC50=70~100 nM). N-Arachidonoylserotonin is analgesic in rodents [1]. |
| Target | IC50: 1~12 µM (FAAH), 70~100 nM (TRPV1 channels) |
| Name | N-Arachidonoylserotonin |
| CAS | 187947-37-1 |
| Formula | C30H42N2O2 |
| Molar Mass | 462.67 |
| Appearance | Liquid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Solution, -20°C, 2 years |
| Reference | [1]. Ortar G, et al. New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain. J Med Chem. 2007;50(26):6554-6569. |
N-Arachidonoylserotonin
CAS: 187947-37-1 F: C30H42N2O2 W: 462.67
N-Arachidonoylserotonin (Arachidonyl serotonin; AA-5-HT) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an
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