N-Acetyl sulfadiazine-d4_product_DataBase

Bioactivity	N-Acetyl sulfadiazine-d4 is the deuterium labeled Triton X-45(n=4). Triton X-45 (n=4), a nonionic surfactant with a low hydrophile-lypophile balance (HLB) value and dispersible in aqueous solution at room temperature, has a Krafft point above the room temperature. Triton X-45 has the potential for the research of the hepatitis C virus (HCV)[1][2].
Invitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Name	N-Acetyl sulfadiazine-d4
CAS	1219149-66-2
Formula	C12H8D4N4O3S
Molar Mass	296.34
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Wang Z, et al. Cloud point of nonionic surfactant Triton X-45 in aqueous solution. Colloids Surf B Biointerfaces. 2008;61(1):118-122. [3]. Chou ML, et al. TnBP⁄Triton X-45 treatment of plasma for transfusion efficiently inactivates hepatitis C virus. PLoS One. 2015;10(2):e0117800. Published 2015 Feb 6.

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