Bioactivity | N-Acetyl dapsone (MADDS) is the major metabolite of Dapsone (HY-B0688). Dapsone is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities[1][2]. |
Name | N-Acetyl dapsone |
CAS | 565-20-8 |
Formula | C14H14N2O3S |
Molar Mass | 290.34 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Tanaka K, et al. Mutagenicity of N-acetyl and N,N'-diacetyl derivatives of 3 aromatic amines used as epoxy-resin hardeners. Mutat Res. 1985 May-Jun;143(1-2):11-5. [2]. Bonde S L, et al. Simultaneous determination of dapsone and its major metabolite N-Acetyl Dapsone by LC-MS/MS method. Int. J. Pharm. Pharm. Sci, 2013, 5: 441-446. |