Bioactivity | N-Acetyl-L-aspartic acid-d3-1is the deuterium labeledN-Acetyl-L-aspartic acid(HY-W710495)[1]. |
Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。 |
Name | N-Acetyl-L-aspartic acid-d3-1 |
CAS | 1383929-94-9 |
Formula | C6H6D3NO5 |
Molar Mass | 178.16 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Benuck M, et al. Acetyl transport mechanisms. Metabolism of N-acetyl-L-aspartic acid in the non-nervous tissues of the rat. Biochim Biophys Acta. 1968 May 1;152(3):611-8. |