N-Acetyl-D-galactosamine, 98%_product_DataBase

Bioactivity

N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans. N-Acetyl-D-galactosamine (GalNAc) interact with Soya bean agglutinin (SBA), hence decreasing the effects of SBA on cellular membrane permeability and tight junction protein expression in piglets[1].N-Acetyl-D-galactosamine (GalNAc) inhibits the hemagglutinating activity by the lectin[2].

Invitro

N-Acetyl-D-galactosamine (GalNAc) (50nm; 4 hours) decreases the expression of occludin mRNA and claudin-3 mRNA by 1.6% and 2.7%[1].N-Acetyl-D-galactosamine (GalNAc) (50nm; 4 hours) lowers the protein expression of occludin and claudin-3 by 4.3% and 7.2%, respectively[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> N-Acetyl-D-galactosamine, 98% 相关抗体: RT-PCR[1] Cell Line:

CAS

14215-68-0

Formula

C8H15NO6

Molar Mass

221.21

Appearance

固体

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Zhao B, et al. N-Acetyl-d-galactosamine prevents soya bean agglutinin-induced intestinal barrier dysfunction in intestinal porcine epithelial cells. J Anim Physiol Anim Nutr (Berl). 2019 Jul;103(4):1198-1206. [2]. Sadanandan R, et al. Isolation, Purification and Characterisation of a D-galactose and N-acetyl-D-galactosamineSpecific Lectin from Marine Sponge Fasciospongia cavernosa. Protein Pept Lett. 2018;25(9):871-877.

PeptideDB

N-Acetyl-D-galactosamine, 98%

CAS: 14215-68-0 F: C8H15NO6 W: 221.21