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N-(4-Anilino-1-naphthyl)maleimide

CAS: 50539-45-2 F: C20H14N2O2 W: 314.34

N-(4-Anilino-1-naphthyl)maleimide is a fluorescent probe that can be used to detect thiol groups in proteins. N-(4-Anili
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Bioactivity N-(4-Anilino-1-naphthyl)maleimide is a fluorescent probe that can be used to detect thiol groups in proteins. N-(4-Anilino-1-naphthyl)maleimide reacts with thiol groups and immediately produces a stable fluorescent compound with the λex=355 nm, λem=448 nm[1].
Invitro N-(4-Anilino-1-naphthyl)maleimide can be used to label rabbit muscle fibers and its fluorescence spectrum reflects their conformational changes between relaxed or contracted states[2].
Name N-(4-Anilino-1-naphthyl)maleimide
CAS 50539-45-2
Formula C20H14N2O2
Molar Mass 314.34
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. T Honda, et al. Characterization of the reactivity of sulphydryl groups in tryptophanase by a dual-monitoring high-performance liquid chromatographic system with a site-directed fluorescent reagent. J Chromatogr. 1986 Dec 26;371:353-60. [2]. S Chaen, et al. Fluorescence properties and contraction characteristics of ANM (N-(1-anilinonaphthyl-4)maleimide)-labeled rabbit psoas muscle fibers. J Biochem. 1985 Oct;98(4):939-47.