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N,N-Dimethylformamide

CAS: 68-12-2 F: C3H7NO W: 73.09

N,N-Dimethylformamide (DMF) is widely used as a drug solvent. N,N-Dimethylformamide is a dipolar protophilic solvent wit
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Bioactivity N,N-Dimethylformamide (DMF) is widely used as a drug solvent. N,N-Dimethylformamide is a dipolar protophilic solvent with physicochemical properties that makes it suitable as solvent for capillary electrophoresis (CE)[1][2].
In Vivo N,N-Dimethylformamide (DMF; N-Formyldimethylamine) has hepatotoxic properties[3].
Name N,N-Dimethylformamide
CAS 68-12-2
Formula C3H7NO
Molar Mass 73.09
Appearance Liquid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
Reference [1]. Porras SP, et al. Capillary electrophoresis in N,N-dimethylformamide. Electrophoresis. 2005;26(17):3279-3291. [2]. Varma RK, et al. Solvent artifacts likely to be induced by dimethylformamide. Indian J Physiol Pharmacol. 1986;30(3):248-254. [3]. Mráz J, et al. Investigation of the mechanistic basis of N,N-dimethylformamide toxicity. Metabolism of N,N-dimethylformamide and its deuterated isotopomers by cytochrome P450 2E1. Chem Res Toxicol. 1993;6(2):197-207.