| Bioactivity | Myosin modulator 1 (Compound B141) is a modulator for myosin, that inhibits ATPase in rabbits psoas, porcine atria and in porcine ventricle, with IC25s of 0.42, 0.13 and 3.09 μM, respectively. Myosin modulator 1 regulates systolic cardiac performance in Sprague Dawley rats[1]. |
| CAS | 3034189-56-2 |
| Formula | C18H14F3N5O2 |
| Molar Mass | 389.33 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hawryluk N, et al., 1,4-dihydroquinazolinone compounds and uses thereof. WO2024073426A1. |
Myosin modulator 1
CAS: 3034189-56-2 F: C18H14F3N5O2 W: 389.33
Myosin modulator 1 (Compound B141) is a modulator for myosin, that inhibits ATPase in rabbits psoas, porcine atria and i
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