| Bioactivity | Mycothiazole is an inhibitor for mitochondrial electron transport chain (ETC) complex I. Mycothiazole exhibits cytotoxicity in cancer cells Huh7 (IC50 is 55.8 μM), U87 and MCF7. Mycothiazole induces apoptosis in Huh7. Mycothiazole utilizes the unfolded protein response (UPR) and heat shock response (HSR) pathway involved transcription factors ATFS-1 and HSF1, to extend the lifespan of C. elegans[1]. |
| CAS | 114582-75-1 |
| Formula | C22H32N2O3S |
| Molar Mass | 404.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dutta N,et al., Investigating impacts of the mycothiazole chemotype as a chemical probe for the study of mitochondrial function and aging. Geroscience. 2024 Apr 3. |
Mycothiazole
CAS: 114582-75-1 F: C22H32N2O3S W: 404.57
Mycothiazole is an inhibitor for mitochondrial electron transport chain (ETC) complex I. Mycothiazole exhibits cytotoxic
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.