| Bioactivity | Muzolimine (BAY-g 282) is a slow and long lasting diuresis agent. Muzolimine produces a diuresis in the loop of Henle and also shows anti-hypertensive effects. Muzolimine can be used for the research of cardiovascular disease[1][2]. |
| Invitro | Muzolimine (10 μM-1 mM) dose-dependently inhibits ion transport in Ehrlich cells[2]. |
| In Vivo | Muzolimine (0-18 mg/kg; p.o. 7-times per week for 3 months) shows a marked diuresis effect in dogs[1]. Animal Model: |
| Name | Muzolimine |
| CAS | 55294-15-0 |
| Formula | C11H11Cl2N3O |
| Molar Mass | 272.13 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lorke D, Mürmann P. Pre-clinical toxicological studies with muzolimine. Curr Med Res Opin. 1976-1977;4(10):716-24. [2]. Geck P, Pfeiffer B. Inhibition of ion transport in Ehrlich cells by muzolimine. Naunyn Schmiedebergs Arch Pharmacol. 1986 Jul;333(3):323-9. |
Muzolimine
CAS: 55294-15-0 F: C11H11Cl2N3O W: 272.13
Muzolimine (BAY-g 282) is a slow and long lasting diuresis agent. Muzolimine produces a diuresis in the loop of Henle an
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