| Bioactivity | Muscone is the main active monomer of traditional Chinese medicine musk. Muscone inhibits NF-κB and NLRP3 inflammasome activation. Muscone remarkably decreases the levels of inflammatory cytokines (IL-1β, TNF-α and IL-6), and ultimately improves cardiac function and survival rate[1]. | ||||||||||||
| Invitro | Muscone significantly downregulates the levels of LPS-induced inflammatory cytokines and inhibits NF-κB and NLRP3 inflammasome activation in Bone marrow-derived macrophages (BMDMs). Muscone serves as a promising and effective drug for post-myocardial infarction (MI) treatment[1]. | ||||||||||||
| Name | Muscone | ||||||||||||
| CAS | 541-91-3 | ||||||||||||
| Formula | C16H30O | ||||||||||||
| Molar Mass | 238.41 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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