| Bioactivity | Muscle homing peptide M12 can preferentially bind to surface protein of muscle cells. Muscle homing peptide M12 mediates enhanced cellular uptake of nanoparticles (NPs) in myoblasts in vitro. Muscle homing peptide M12 is covalently conjugated to PLGA-PEG NPs via the N-terminal α-amino groups of peptides using the N-hydroxysuccinimide ester reaction[1][2]. |
| CAS | 2896181-32-9 |
| Sequence | Arg-Arg-Gln-Pro-Pro-Arg-Ser-Ile-Ser-Ser-His-Pro |
| Shortening | RRQPPRSISSHP |
| Formula | C59H100N24O17 |
| Molar Mass | 1417.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gun-Jae Jeong, et al. Nanomaterial for Skeletal Muscle Regeneration. Tissue Eng Regen Med. 2022 Apr;19(2):253-261. [2]. Di Huang, et al. Polymeric nanoparticles functionalized with muscle-homing peptides for targeted delivery of phosphatase and tensin homolog inhibitor to skeletal muscle. Acta Biomater. 2020 Dec:118:196-206. |
Muscle homing peptide M12
CAS: 2896181-32-9 F: C59H100N24O17 W: 1417.58
Muscle homing peptide M12 can preferentially bind to surface protein of muscle cells. Muscle homing peptide M12 mediates
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