Muscarine tosylate_product_DataBase

Bioactivity	Muscarine ((+)-Muscarine) tosylate is an agonist of prototype mAChR. Muscarine tosylate is a toxin that can stimulate the parasympathetic nervous system[1][2].
Invitro	在脑微血管内皮细胞和小鼠脑微血管内皮细胞中，Muscarine tosylate (100 µM) 诱导的细胞内钙信号振幅与 10 µM 乙酰胆碱触发的信号振幅相似[1]。Muscarine tosylate (1-30 μM；2 分钟) 在中缝大核 (NRM) 神经元神经元上含有 5-羟色胺 (5-HT) 的 NRM 细胞亚群中产生剂量依赖性超极化，EC50 值为 2.7 µM[2]。 0 --> Muscarine tosylate 相关抗体:
Name	Muscarine tosylate
CAS	82083-43-0
Formula	C16H27NO5S
Molar Mass	345.45
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Beatrice Mihaela Radu, et al. All muscarinic acetylcholine receptors (M 1-M 5) are expressed in murine brain microvascular endothelium. Sci Rep. 2017 Jul 11;7(1):5083. [2]. Z Z Pan, et al. Muscarine hyperpolarizes a subpopulation of neurons by activating an M2 muscarinic receptor in rat nucleus raphe magnus in vitro. J Neurosci. 1994 Mar;14(3 Pt 1):1332-8.

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