Bioactivity | MurB-IN-1 (compound 44) is an inhibitor of uridine diphosphate-N-acetylenolpyruvylglucosamine reductase (MurB), with a Kd 3.57 μM. MurB, a target in P. aeruginosa, is an opportunistic infectious agent causing death[1]. |
Name | MurB-IN-1 |
Formula | C12H7Cl2F3N2O2 |
Molar Mass | 339.10 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Acebrón-García-de-Eulate M, et, al. Discovery of Novel Inhibitors of Uridine Diphosphate- N-Acetylenolpyruvylglucosamine Reductase (MurB) from Pseudomonas aeruginosa, an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients. J Med Chem. |