| Bioactivity | MurA-IN-2 (compound 37), a chloroacetamide fragment containing a primary aliphatic amine, is a potent MurA inhibitor with an IC50 value of 39 μM. MurA-IN-2 has antibacterial activity and inhibits the bacterial cell wall synthesis[1]. |
| Target | IC50: 39 μM (MurA) |
| Invitro | MurA-IN-2 (compound 37; 128 μg/mL) inhibits bacteria S. aureus ATCC29213 and E. coli ATCC25922 activity[1]. |
| Name | MurA-IN-2 |
| CAS | 2164447-18-9 |
| Formula | C12H20ClNO |
| Molar Mass | 229.75 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Grabrijan K, et, al. Covalent inhibitors of bacterial peptidoglycan biosynthesis enzyme MurA with chloroacetamide warhead. Eur J Med Chem. 2022 Sep 13; 114752. |
MurA-IN-2
CAS: 2164447-18-9 F: C12H20ClNO W: 229.75
MurA-IN-2 (compound 37), a chloroacetamide fragment containing a primary aliphatic amine, is a potent MurA inhibitor wit
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