| Bioactivity | Mu opioid receptor antagonist 4 (compound 31) is a potent and selective μ opioid receptor (MOR) antagonist with a Ki of 0.38 nM and an EC50 of 1.07 nM. Mu opioid receptor antagonist 4 has remarkable CNS antagonism against morphine, and precipitated fewer withdrawal symptoms than Naloxone. Mu opioid receptor antagonist 4 Mu opioid receptor antagonist 4 can be used for researching opioid use disorders (OUD)[1]. |
| Target | EC50: 1.07 nM (MOR)Ki: 0.38 nM (MOR) |
| Name | Mu opioid receptor antagonist 4 |
| Formula | C25H28N2O4S |
| Molar Mass | 452.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pagare PP, et al. Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists. J Med Chem. 2022;65(6):5095-5112. |
Mu opioid receptor antagonist 4
CAS: F: C25H28N2O4S W: 452.57
Mu opioid receptor antagonist 4 (compound 31) is a potent and selective μ opioid receptor (MOR) antagonist with a Ki of
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.