| Bioactivity | Mtb-cyt-bd oxidase-IN-6 is a potent Mycobacterium tuberculosis (Mtb) cytochrome bd (cyt-bd) oxidase (MtbCyt-bd Oxidase) inhibitor with an IC50 value of 0.35 μM. Mtb-cyt-bd oxidase-IN-6 can effectively inhibit the growth of Mtb (MIC= 4 μM). Mtb-cyt-bd oxidase-IN-6 can be used in the study of tuberculosis[1]. |
| Target | IC50: 0.37 μM (MtbCyt-bd Oxidase) |
| Invitro | Mtb-cyt-bd oxidase-IN-5 (compound 1d; 0-2048 μM; 7 days) inhibits growth of M. tuberculosis with a MIC value of 256 μM[1]. |
| Name | Mtb-cyt-bd oxidase-IN-6 |
| Formula | C20H27NO |
| Molar Mass | 297.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lawer A, et, al. Synthesis and Biological Evaluation of Aurachin D Analogues as Inhibitors of Mycobacterium tuberculosis Cytochrome bd Oxidase. ACS Med Chem Lett. 2022 Sep 26;13(10):1663-1669. |
Mtb-cyt-bd oxidase-IN-6
CAS: F: C20H27NO W: 297.43
Mtb-cyt-bd oxidase-IN-6 is a potent Mycobacterium tuberculosis (Mtb) cytochrome bd (cyt-bd) oxidase (MtbCyt-bd Oxidase)
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