| Bioactivity | Mtb-cyt-bd oxidase-IN-5 (compound 1k) is a Mycobacterium tuberculosis (Mtb) cytochrome bd (cyt-bd) oxidase (MtbCyt-bd Oxidase) inhibitor with an IC50 value of 0.37 μM. Mtb-cyt-bd oxidase-IN-5 can effectively inhibit the growth of Mtb (MIC= 256 μM). Mtb-cyt-bd oxidase-IN-5 can be used in the study of tuberculosis[1]. |
| Invitro | Mtb-cyt-bd oxidase-IN-5 (0-2048 μM; 7 days) inhibits growth of M. tuberculosis (MIC=256 μM)[1]. Cell Viability Assay[1] Cell Line: |
| Name | Mtb-cyt-bd oxidase-IN-5 |
| Formula | C25H32FNO |
| Molar Mass | 381.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lawer A, et al. Synthesis and Biological Evaluation of Aurachin D Analogues as Inhibitors of Mycobacterium tuberculosis Cytochrome bd Oxidase. ACS Med Chem Lett. 2022 Sep 26;13(10):1663-1669. |
Mtb-cyt-bd oxidase-IN-5
CAS: F: C25H32FNO W: 381.53
Mtb-cyt-bd oxidase-IN-5 (compound 1k) is a Mycobacterium tuberculosis (Mtb) cytochrome bd (cyt-bd) oxidase (MtbCyt-bd Ox
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