| Bioactivity | MtTMPK-IN-4 (compound 2), a para-piperidine, is a potent mycobacterium tuberculosis thymidylate kinase (MtTMPK) inhibitor with an IC50 of 6.1 μM. MtTMPK-IN-4 is a potent tyrosinase inhibitor. MtTMPK-IN-4 is a potent antibacterial agent[1][2]. |
| Name | MtTMPK-IN-4 |
| CAS | 2225889-49-4 |
| Formula | C23H25N3O3 |
| Molar Mass | 391.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lijun Song, et al. Structure Guided Lead Generation toward Nonchiral M. tuberculosis Thymidylate Kinase Inhibitors. J Med Chem. 2018 Apr 12;61(7):2753-2775. [2]. Jin Li, et al. Recent advances in the design and discovery of synthetic tyrosinase inhibitors. Eur J Med Chem. 2021 Nov 15;224:113744. |