| Bioactivity | MtTMPK-IN-2 (compound 15) is a potent Mycobacterium tuberculosis thymidylate kinase (MtTMPK) inhibitor with an IC50 value of 1.1 μM. MtTMPK-IN-2 has inhibitory activity against Mtb H37Rv (MIC = 12.5 μM). MtTMPK-IN-2 exhibits certain cytotoxicity in human fibroblast cells MRC-5 (EC50 = 6.1 μM). MtTMPK-IN-2 can be used for researching tuberculosis[1]. |
| Target | IC50: 1.1 μM (MtTMPK) |
| Name | MtTMPK-IN-2 |
| CAS | 2799607-71-7 |
| Formula | C23H24ClN3O3 |
| Molar Mass | 425.91 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Song L, et al. Structure-aided optimization of non-nucleoside M. tuberculosis thymidylate kinase inhibitors. Eur J Med Chem. 2021;225:113784. |
MtTMPK-IN-2
CAS: 2799607-71-7 F: C23H24ClN3O3 W: 425.91
MtTMPK-IN-2 (compound 15) is a potent Mycobacterium tuberculosis thymidylate kinase (MtTMPK) inhibitor with an IC50 valu
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.