| Bioactivity | Mt KARI-IN-5 (compound 6c) is a potent Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI) inhibitor with a Ki value of 4.72 μM. Mt KARI-IN-5 has inhibitory activity against Mtb H37Rv (MIC = 1.56 μM) and low cytotoxicity (HEK IC50 > 64 μg/mL)[1] |
| Target | Ki: 4.72 μM (Mtb KARI) |
| Name | Mt KARI-IN-5 |
| CAS | 2413974-69-1 |
| Formula | C14H10N4O5S3 |
| Molar Mass | 410.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Krishna VS, et al. Design and development of ((4-methoxyphenyl)carbamoyl) (5-(5-nitrothiophen-2-yl)-1,3,4-thiadiazol-2-yl)amide analogues as Mycobacterium tuberculosis ketol-acid reductoisomerase inhibitors. Eur J Med Chem. 2020;193:112178. |
Mt KARI-IN-5
CAS: 2413974-69-1 F: C14H10N4O5S3 W: 410.45
Mt KARI-IN-5 (compound 6c) is a potent Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI) inhibitor with
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.