| Bioactivity | MraY-IN-1 (compound 12a) is a potent MraY inhibitor with an IC50 value of 140 μM. MraY-IN-1 has antimicrobial activity against Escherichia coli K12, Bacillus subtilis W23 and Pseudomonas fluorescens Pf-5 with MIC50s of 7 µg/mL, 12 µg/mL and 46 µg/mL, respectively. MraY-IN-1 can be used for researching anti-bacteria[1]. |
| Target | IC50: 140 μM (MraY) |
| Name | MraY-IN-1 |
| Formula | C35H46N3O5+ |
| Molar Mass | 588.76 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kerr RV, et al. Peptidomimetic analogues of an Arg-Trp-x-x-Trp motif responsible for interaction of translocase MraY with bacteriophage ϕX174 lysis protein E. Bioorg Med Chem. |