Morachalcone A_product_DataBase

Bioactivity	Morachalcone A is a naturally-occurring aromatase inhibitor (IC50=4.6 mM). Morachalcone A is also a plants metabolite with potential anti-inflammatory and anticancer activity. Morachalcone A inhibits Lipopolysaccharide (HY-D1056)-induced nitric oxide production[1][2][3].
Invitro	Morachalcone A 是 Maclura pomifera(奥色橘树)、Hypericum Geminiflorum 和 Broussonetia papyrifera 的代谢物[1]。Morachalcone A 在体外培养的 RAW 264.7 细胞中对脂多糖诱导的一氧化氮产生有抑制作用[2]。
Name	Morachalcone A
CAS	76472-88-3
Formula	C20H20O5
Molar Mass	340.37
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Brandt D R, et al. The synthetic preparation of naturally-occurring aromatase inhibitors, morachalcone A, isogemichalcone B, and isogemichalcone C[J]. Tetrahedron, 2013, 69(47): 9994-10002. [2]. Kang Y J, et al. Inhibitory effects of morachalcone A on lipopolysaccharide-induced nitric oxide production in raw 264.7 cells[J]. 2009. [3]. Ferlinahayati, et al. Phenolic constituents from the wood of Morus australis with cytotoxic activity. Z Naturforsch C J Biosci. 2008 Jan-Feb;63(1-2):35-9.

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