| Bioactivity | Monomethyl auristatin E intermediate-9 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1]. | ||||||||||||
| Name | Monomethyl auristatin E intermediate-9 | ||||||||||||
| CAS | 120205-58-5 | ||||||||||||
| Formula | C22H35NO5 | ||||||||||||
| Molar Mass | 393.52 | ||||||||||||
| Appearance | 油状物 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Lisa Buckel, et al. Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery. Cancer Res. 2015 Apr 1;75(7):1376-87. |
Monomethyl auristatin E intermediate-9
CAS: 120205-58-5 F: C22H35NO5 W: 393.52
Monomethyl auristatin E intermediate-9 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162)
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