Bioactivity | Monomethyl auristatin E (MMAE) (Standard) is the analytical standard of Monomethyl auristatin E (HY-15162). This product is intended for research and analytical applications. Monomethyl auristatin E is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types. |
CAS | 474645-27-7 |
Formula | C39H67N5O7 |
Molar Mass | 717.98 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |